PolyPeptide相关论文
Nanoengineered polypeptides from tetraphenylethylene-functionalized N-carboxyanhydride:Synthesis,sel
Ring-opening polymerization of N-carboxyanhydrides (NCAs) bearing pendant groups creates functional poly-peptides.In thi......
Co-delivery of siRNA and docetaxel into tumor by polypeptide micelles based on PEG-PLL-PLLeu tribloc
Combination of two or more therapeutic strategies with different mechanisms can cooperatively impede cancer development.......
Smart polymeric carriers recently attained much attention in the development of drug delivery system especially for the ......
PEG-polypeptide conjugated with LHRH as an efficient vehicle for targeted delivery of doxorubicin to
Nano-scaled drug delivery systems have been attracting great attention in cancer therapy due to their great advantages o......
Synthetic polypeptides inherit many intriguing properties of proteins such as excellent biocompatibility,biodegradabilit......
Biodegradable poly(ethylene glycol) methyl ether acrylate-b-poly(L-lysine)-b-poly(L-histidine) tribl
The development of biodegradable cationic polymers for gene delivery is desirable to circumvent the drawbacks of the vir......
Polypeptides are functional biomolecules that play a key role in life science, where they can act as hormones and signal......
Phenylboronic Acid Functionalized Polypeptide Micelles for Glucose-Responsive Insulin Release at Phy
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Caged mPEG-Poly(S-(2-nitrobenzyl)-L-cysteine) for Photo-Triggered Drug Release and Thiol-Ene Functio
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Well-defined peptide-conjugated intracellular-acidity-sensitive nanoassemblies for tumor-targeted an
Cell-penetrating peptides (CPPs),comprised of short cationic or amphipathic peptides,have the ability to enhance the cel......
Phenylboronic acid-functionalized polypeptide nanogel for glucose-sensitive drug release under physi
Synthetic polypeptides,which are biocompatible and biodegradable,have been extensively investigated for various biomedic......
NIR Light-actuated Gold Nanorods With Cisplatin-Polypeptide Wrapping for Targeted Therapy of Metasta
Uncontrolled growth and metastasis are two fatal hallmarks of malignant tumors,which represent the dominant challenges f......
Phenylboronic acid-functionalized polypeptide nanogel for glucose-responsive insulin release under p
Biocompatible and biodegradable synthetic polypeptides have been widely studied for various biomedical applications,such......
Novel reversibly crosslinked chimaeric polypeptide polymersomes for active loading and intracellular
The disulfide-crosslinking approach has shown to elegantly resolve the extracellular stability and intracellular drug re......
R8-modified polysarcosine-b-polylysine polypeptide to enhance circulation stability and gene deliver
Recently,polypeptides have been extensively researched as gene/drug delivery system for its similar structure to natural......
Synthesis of Water-Soluble, Stable Helical Polypeptide-Grafted Cyclodextrin Bioconjugates with Guest
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To accelerate the drug release profile,dual or multi stimuli-responsive nanocarriers are promising candidates for the ac......
Reduction and pH Dual-Sensitive Core-Crosslinked Polypeptide Micelles for Triggered Doxorubicin Rele
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Facile Preparation of pH and Reduction Responsive PEGylated Polypeptide Nanogel for Efficient Doxoru
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Tacrolimus(FK506)is an immunosuppressive agent which is usually applied to patients who received allotransplantation to ......
Polypeptide Micelles Delivered Suicide Gene Effectively Inhibited Hepatoma Cancer Cells Proliferatio
Gene therapy can be defined as the transfer of genetic material into a cell for therapeutic purposes.Cytosine deaminase ......
MHC(major histocompatibility complex)class I complex structure reveals the antigen-binding pockets and suitable peptides......
Protein is the construction unit of life bodies and the carrier of life activities,which is composed of amino acid resid......
基于多肽(Polypeptides PC2～PC6)中富有巯基(-SH)官能团, 其与单溴二胺(Monobromobimanes mBBr)能够发生缩合反应, 生成具有荧光信......
目的探寻与卵巢癌诊断相关的血清循环多肽标志物。方法以2018年3月至2018年9月中国医学科学院肿瘤医院妇瘤科收治的原发卵巢上皮癌......
Artificial enzyme was constructed by attaching short peptides with active sites (SHELKLKLKL,WLKLKLKL) on carbon nano......
A novel pH-and thermo-responsive block copolymer based on polypeptide was synthesized by ring-opening polymerization......
化疗是恶性肿瘤最常见和最重要的治疗途径之一。虽然近年来不断有新的抗肿瘤药物出现，且治疗方案也不断改进，然而，临床上仍存在药物靶......
慢性肾功能衰竭患者,恶性肿瘤的发生率增加。作者研究93例慢性血透患者,发现肿瘤标志物组织多肽抗原(tissue polypeptide antigen......
用多肽“阻隔”木质素是一种减少纤维素酶无效结合的新技术。本研究设计了10个多肽序列并构建了三维模型,其中序列FPLGPNHTNPSF与......
刺激响应聚多肽是一类能够在外界刺激下发生物理形态或化学组成变化的高分子材料。本文介绍了聚多肽的合成方法，并从氧化还原、温度......
<正> Glucagon is a polypeptide hormone of 29 amino acids which is synthesized by the α-cell of the islets of Langerhans......
越过油水的很多潜在的摆动连接 ahve 由在油阶段(硝基苯答案) 在水的阶段和各种各样的氨基酸或甚至多肽使用各种各样的表面活化剂......
Effects of Photosystem Ⅱ (PS Ⅱ) extrinsic polypeptides of oxygen-evolving complex and manganese clusters on PS Ⅱ carb......
The lattice theory regarding ternary systems involving a conformationally variable polypeptide and a randomly coiled pol......
The relative energies of polypeptide conformers predicted by linear scaling second-order M?ller-Ples
We describe an implementation of the cluster-in-molecule(CIM) resolution of the identity(RI) approximation second-order ......
Polypeptide Brushes Grown via Surface-initiated Ring-opening Polymerization of α-Amino Acid N-Carbox
Polypeptide brushes are attractive platforms to generate functional and responsive interfaces that are of potential inte......
Peptides/proteins aggregation can give rise to pathological conditions of many human diseases.Small partially ordered ol......
Objective To investigate the expression of apelin and its recoptor (APJ) in myocardium in insulin-resistant CIR rats wit......
Chemistry of trichosanthin IV.The main amino acid sequence of proposed principle primary structure o
In previous paper~(1-3)were reported the physical and chemical properties,the deter-mination of the N-terminal amino ac......
In this paper the synthesis of α-human atrial natriuretic polypeptide fragments (positions, 1-4, 5-10, 11-16, 17-22, 2......
The dynamic changes of protein polypeptide in endosperms of Gingkgo biloba seeds during seed germination were studied by......
Association of genetic variability in glucose-dependent insulinotropic polypeptide receptor and coro
Objective To investigate the relationship between glucose-dependent insulinotropic polypeptide receptor(GIPR)gene polymo......
Shanxi Yongji Sino Agri Chemical Company Limited,a subsidiary of China Agriculture Production Materials Group Corporati......
A method for labeling polypeptide (insulin) with technetium- 99(99mTc) was established without marked loss of biological......
A novel polypeptide having stimulant effect on some cell proliferation was isolated from the velvet antler (Cervus elaph......
Arsenazo M could bind with bovine serum albumin to form a complex in Clark-Lube buffer at pH 2.3 and room temperature, w......
Experimental study on therapeutic effect of in vivo expression of Cell Ⅰ-Hep Ⅱ recombinant polypepti
AIM:To investigate the inhibitory effect of in vivoexpressionof expressing plasmid pCH510 of recombinant fibronectinpol......
目的:研究市售不同来源福林试剂对肌氨肽苷注射液中多肽含量测定结果的影响.方法:采用福林酚法测定多肽的含量;以牛血清白蛋白为对......
目的 预测并鉴定新的人乙酰肝素酶(Hpa)抗原的HLA-A2限制性CTL表位,为恶性肿瘤多肽疫苗的免疫治疗提供依据. 方法 采用SYFPEITHI和......
